20 min walk from Eastener - "Berlin Dom"

to Bahnhof Friedrichstrasse:

from Hbf (central station):
DIRECTLY TO THE HOSTEL the best is to take a cab (5 minutes, 6 Euro), take the bus 142 (4 stops to the hostel) or take any S-Bahn to Friedrichstrasse (1 stop)

from Bhf. Ostbahnhof:
take every S-Bahn to Friedrichstrasse (4 stops)
(S3 Westkreuz, S5 Spandau, S7 Potsdam, S9 Westkreuz)

from Bhf. Lichtenberg:
take the S-Bahn to Friedrichstrasse (8 stops)
(S5 Spandau, S7 Potsdam)

Airport Schoenefeld (SXL):
take the S-Bahn to Friedrichstrasse (appr. 40 minutes)

Airport Tegel (TXL):
take the bus number 128 until U-Bf Kurt-Schumacher-Platz then change into underground U 6 until Oranienburger Tor (9 stops) and follow the descriptions on the platform

from Bahnhof Friedrichstrasse:

then change to Underground U6 direction Alt-Tegel to Oranienburger Tor (1 stop)

exit same direction train goes (not if you come from Airport Tegel, then you must take the opposite exit)

keep walking 100 m on right side, pass the famous Oranienburger Strasse and take a right on the second

cross into Torstrasse, keep walking and after 100 m take a left on the first into Novalisstrasse and watch for the sign "HOSTEL"